https://dspace.ncfu.ru/handle/20.500.12258/52 Thu, 05 Mar 2026 02:45:07 GMT 2026-03-05T02:45:07Z https://dspace.ncfu.ru/handle/123456789/32644 Title: Organic Chemistry in the Creation of Molecules with Practically Useful Properties Authors: Aksenov, A. V.; Аксенов, А. В.; Aksenov, D. A.; Аксенов, Д. А.; Aksenov, N. A.; Аксенов, Н. А.; Dotsenko, V. V.; Доценко, В. В. Abstract: : Organic compounds have the widest practical application, and the methodology of their synthesis is often developed specifically to solve applied problems in medicinal chemistry, catalysis, materials chemistry, agriculture, food industry, and the creation of electronic and sensor devices. This is due to the huge variety of properties and functional capabilities of organic substances, as well as the ability to fine-tune their structure to impart certain practically useful characteristics. Currently, the number of organic compounds used in various fields of industry, medicine, and agriculture is in the hundreds of thousands, and their number continues to grow steadily due to the rapid development of synthetic organic chemistry and predictive methods for determining properties, including using artificial intelligence. This collective review is devoted to the achievements of Russian chemists in the field of practically oriented organic chemistry over the past 5–10 years. The review presents the achievements of leading research teams representing both RAS institutes and Russian universities, from Kaliningrad to Siberia. Thu, 01 Jan 2026 00:00:00 GMT https://dspace.ncfu.ru/handle/123456789/32644 2026-01-01T00:00:00Z https://dspace.ncfu.ru/handle/123456789/32643 Title: Synthesis of 7a,8-Dihydrobenzo[5,6]chromeno[2,3-b]pyrrol-9(11H)-ones Authors: Demidov, O. P.; Демидов, О. П. Abstract: A method for the synthesis of 7a,8-dihydrobenzo[5,6]chromeno[2,3-b]pyrrol-9(11H)-ones from β-methoxalyl-substituted 1H-benzo[f]chromenes and primary aliphatic amines in the presence of nitromethane has been developed. A possible reaction route is proposed that includes the Henry reaction, the aza-Michael reaction, intramolecular nucleophilic addition, and the retro-aza-Henry reaction as the main stages. Thu, 01 Jan 2026 00:00:00 GMT https://dspace.ncfu.ru/handle/123456789/32643 2026-01-01T00:00:00Z https://dspace.ncfu.ru/handle/123456789/32642 Title: [3+3]-Cyclocondensation of β-Carbonyl-Substituted 4H-Chromenes with 3- and 6-Aminoindazoles: Synthesis of Pyrimido[1,2-b]indazoles and Pyrazolo[3,4-f]quinolines Authors: Demidov, O. P.; Демидов, О. П. Abstract: A method for the synthesis of pyrazolo[3,4-f]quinolines from 6-aminoindazole and 4H-chromene-3-carbaldehydes or their fused analogs has been developed. It has been established that the reaction of β-trifluoroacetyl-substituted 4H-chromenes with 6-aminoindazole proceeds regioselectively to afford 9-trifluoromethylpyrazolo[3,4-f]quinolines. It has also been demonstrated that in reactions with 4H-chromene-3-carbaldehydes or 1H-benzo[f]chromene-2-carbaldehydes, 3-aminoindazoles act as 1,3-N,N-binucleophiles, thereby providing access to pyrimido[1,2-b]indazoles. Thu, 01 Jan 2026 00:00:00 GMT https://dspace.ncfu.ru/handle/123456789/32642 2026-01-01T00:00:00Z https://dspace.ncfu.ru/handle/123456789/32641 Title: Fall and fingering of miscible magnetic fluid drops in a Hele-Shaw cell Authors: Chernyshov, A. V.; Чернышов, А. В.; Zakinyan, A. R.; Закинян, А. Р. Abstract: The presented study is the experimental and numerical investigation of the fall and fingering of miscible magnetic fluid drops with variable properties in a vertical Hele-Shaw cell under a uniform field normal to the cell plane. We revealed that fingering is possible in magnetic fields that exceed the critical value. For the kerosene-based magnetic fluid used in the experiment and a droplet with a radius of about 3 mm, the critical value of the magnetic field strength was about 2 kA/m. It was found numerically that the distance between the fingers is linearly related to the width of the gap in the Hele-Shaw cell, and for the studied cases it is described by the expression λ = 1.19δ for the magnetic field of about 15 kA/m. The distance between the fingers decreases with the increase of the magnetic field in the region of weak magnetic fields, and with a further increase of the magnetic field, it hardly changes. The velocity of the droplet fall is determined by its morphology. With an increase in the number of fingers, the velocity of the fall decreases significantly. With the maximum value of the parameters numerically studied, the fall velocity decreased 2.5 times. As the number of fingers increases, the rate of mixing of magnetic fluid with the environment increases sharply. During the drop-fall time, the maximum concentration of magnetic fluid decreased 4 times at the maximum value of the parameters studied. However, in the absence of a magnetic field, without fingering, it remained practically unchanged. Thu, 01 Jan 2026 00:00:00 GMT https://dspace.ncfu.ru/handle/123456789/32641 2026-01-01T00:00:00Z