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https://dspace.ncfu.ru/handle/20.500.12258/10019
Title: | Facile regiodivergent synthesis of spiro pyrrole-substituted pseudothiohydantoins and thiohydantoins via reaction of [e]-fused 1H-pyrrole-2,3-diones with thiourea |
Authors: | Rubin, M. A. Рубин, М. А. |
Keywords: | Nitrogen heterocycles;Rearrangement;Diversity-oriented synthesis;Hydantoin;Thiourea |
Issue Date: | 2019 |
Publisher: | Beilstein-Institut |
Citation: | Kobelev, AI; Tretyakov, NA; Stepanova, EE; Dmitriev, MV; Rubin, M; Maslivets, AN. Facile regiodivergent synthesis of spiro pyrrole-substituted pseudothiohydantoins and thiohydantoins via reaction of [e]-fused 1H-pyrrole-2,3-diones with thiourea // BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. - 2019. - Том: 15. - Стр.: 2864-2871 |
Series/Report no.: | Beilstein Journal of Organic Chemistry |
Abstract: | A highly divergent synthesis of regioisomeric thiohydantoins and pseudothiohydantoins spiro-fused to a pharmacologically valuable pyrrole-2-one fragment involving the reaction of [e]-fused 1H-pyrrole-2,3-diones with thioureas was developed. The obtained spiro pseudothiohydantoin derivatives were found to undergo a pseudothiohydantoin-thiohydantoin rearrangement. The reactions were shown to proceed under catalyst-free conditions in good yields, and the products were isolated without applying preparative chromatography methods |
URI: | http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=14&SID=C5tCb5mJo32occO9TBf&page=1&doc=1 http://hdl.handle.net/20.500.12258/10019 |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
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WoS 740 .pdf Restricted Access | 777.44 kB | Adobe PDF | View/Open | |
scopusresults 1151 .pdf Restricted Access | 64.15 kB | Adobe PDF | View/Open |
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