Please use this identifier to cite or link to this item:
https://dspace.ncfu.ru/handle/20.500.12258/12117
Title: | Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis |
Authors: | Rubin, M. A. Рубин, М. А. |
Keywords: | Cycloaddition Reaction;Cyclopropenes;Vinylcarbene |
Issue Date: | 2020 |
Publisher: | American Chemical Society |
Citation: | Yamanushkin, P., Smith, S.P., Petillo, P.A., Rubin, M. Cyclopropene-Templated Assembly of Medium Cycles via Ru-Catalyzed Ring-Closing Metathesis // Organic Letters. - 2020. - Volume 22. - Issue 9. - Pages 3542-3546 |
Series/Report no.: | Organic Letters |
Abstract: | An expeditious click-click cyclize strategy for the assembly of medium-sized heterocyclic rings is described. The sequence involves the reaction of cycloprop-2-ene carboxylic acids with unsaturated amines to furnish amides, which are further subjected to a Cu-catalyzed directed carbomagnesiation and a ring-closing olefin metathesis reaction. This methodology allows for the efficient preparation of lactams with ring sizes up to 10 |
URI: | http://hdl.handle.net/20.500.12258/12117 |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
File | Description | Size | Format | |
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scopusresults 1283 .pdf Restricted Access | 63.61 kB | Adobe PDF | View/Open | |
WoS 830 .pdf Restricted Access | 191.68 kB | Adobe PDF | View/Open |
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