Oxidative rearrangement of 2-(2-Aminobenzyl)furans: synthesis of functionalized indoles and carbazoles

Abstract

2-(2-Acylvinyl)indoles obtained by oxidative rearrangement of substituted 2-(2-aminobenzyl)furans could be used to construct structural analogues of antifungal alkaloids caulindoles A−D as well as other indole-derived molecules and substituted carbazoles by introducing new reaction centers into the structure of starting materials or by synthetic manipulation with functional groups of the obtained compounds