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DC Field | Value | Language |
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dc.contributor.author | Dotsenko, V. V. | - |
dc.contributor.author | Доценко, В. В. | - |
dc.contributor.author | Aksenov, N. A. | - |
dc.contributor.author | Аксенов, Н. А. | - |
dc.contributor.author | Aksenova, I. V. | - |
dc.contributor.author | Аксенова, И. В. | - |
dc.contributor.author | Shcherbakov, S. V. | - |
dc.contributor.author | Щербаков, С. В. | - |
dc.contributor.author | Ovcharov, S. N. | - |
dc.contributor.author | Овчаров, С. Н. | - |
dc.date.accessioned | 2021-03-23T12:27:24Z | - |
dc.date.available | 2021-03-23T12:27:24Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Bibik, I.V., Bibik, E.Y., Dotsenko, V.V., Frolov, K.A., Krivokolysko, S.G., Aksenov, N.A., Aksenova, I.V., Shcherbakov, S.V., Ovcharov, S.N. Synthesis and analgesic activity of new heterocyclic cyanothioacetamide derivatives // Russian Journal of General Chemistry. - 2021. - Volume 91. - Issue 2. - Pages 154-166 | ru |
dc.identifier.uri | http://hdl.handle.net/20.500.12258/15557 | - |
dc.description.abstract | The reaction of cyanothioacetamide with aromatic aldehydes and 1,3-dicarbonyl compounds followed by aminomethylation or S-alkylation gave a series of heterocyclic derivatives with a 1,2,3,4-tetrahydropyridine or 1,4,5,6,7,8-hexahydroquinoline fragment. The resulting compounds were tested for analgesic activity in vivo. Some of the prepared compounds showed an antinociceptive effect superior to that of ketorolac in dynamics | ru |
dc.language.iso | en | ru |
dc.publisher | Pleiades journals | ru |
dc.relation.ispartofseries | Russian Journal of General Chemistry | - |
dc.subject | 2-oxo-3-cyano-1,4,5,6-tetrahydropyridine-2-thiolates | ru |
dc.subject | Analgesics | ru |
dc.subject | Cyanothioacetamide | ru |
dc.subject | Mannich reaction | ru |
dc.subject | Pyrido[2,1-b][1,3,5]thiadiazines | ru |
dc.title | Synthesis and analgesic activity of new heterocyclic cyanothioacetamide derivatives | ru |
dc.type | Статья | ru |
vkr.inst | Химико-фармацевтический факультет | ru |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
File | Description | Size | Format | |
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scopusresults 1613 .pdf Restricted Access | 783.49 kB | Adobe PDF | View/Open | |
WoS 1049 .pdf Restricted Access | 188.94 kB | Adobe PDF | View/Open |
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