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Title: Electrophilically activated nitroalkanes in synthesis of 3,4-dihydroquinozalines
Authors: Aksenov, A. V.
Аксенов, А. В.
Grishin, I. Y.
Гришин, И. Ю.
Aksenov, N. A.
Аксенов, Н. А.
Malyuga, V. V.
Малюга, В. В.
Aksenov, D. A.
Аксенов, Д. А.
Rubin, M. A.
Рубин, М. А.
Keywords: Annulation;Quinozalines;Heterocyclic compounds;Nitroalkanes
Issue Date: 2021
Publisher: MDPI AG
Citation: Aksenov, A.V., Grishin, I. Y., Aksenov, N. A., Malyuga, V. V., Aksenov, D. A., Nobi, M. A., Rubin, M. A. Electrophilically activated nitroalkanes in synthesis of 3,4-dihydroquinozalines // Molecules. - 2021. - Том 26. - Выпуск 142. - Номер статьи 4274
Series/Report no.: Molecules
Abstract: Nitroalkanes activated with polyphosphoric acid serve as efficient electrophiles in reactions with various nucleophilic amines. Strategically placed second functionality allows for the design of annulation reactions enabling preparation of various heterocycles. This strategy was employed to develop an innovative synthetic approach towards 3,4-dihydroquinazolines from readily available 2-(aminomethyl)anilines
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

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