Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/18602
Title: Ultrasonic-treated fucoidan as a promising therapeutic agent
Authors: Suprunchuk, V. E.
Супрунчук, В. Е.
Keywords: Antioxidant activity;Ultrasonic treatment;Depolymerization;Fucoidan;Ultrasonic extraction;Molecular weight
Issue Date: 2021
Publisher: NLM (Medline)
Citation: Suprunchuk, V. E. Ultrasonic-treated fucoidan as a promising therapeutic agent // Polimery w medycynie. - 2021. - Том 51. - Выпуск 2. - Стр.: 85 - 90. - DOI10.17219/pim/143961
Series/Report no.: Polimery w medycynie
Abstract: Fucoidans represent the sulfated heteropolysaccharides that possess a wide range of important pharmacological properties. The properties of a fucoidan depend on several factors, including the molecular weight and the way of extraction. However, the selection of an optimal depolymerization method is necessary to enhance its therapeutic applications. Reducing the molecular weight of fucoidans will make it possible to use them in creating nanoparticles and nanocarriers for, among others, the targeted drug delivery. The molecular mass of the polymer can be changed by means of various methods of depolymerization. In this work, the possibility of application of ultrasonic destruction for decrease in the size of fucoidan molecules for the purpose of expansion of opportunities and spheres of their therapeutic application is considered. This is one of the simple and effective methods of depolymerization of fucoidan, which leads to a decrease in molecular weight without significant structural changes in macromolecules. In addition, methods and potential applications of the ultrasonic extraction of fucoidan from seaweed and the possibilities of their combination are discussed, as well as other physical or chemical methods of extraction.
URI: http://hdl.handle.net/20.500.12258/18602
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

Files in This Item:
File SizeFormat 
scopusresults 2024 .pdf
  Restricted Access
1.34 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.