Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/23489
Title: Alkyl 4-Aryl-6-amino-7- phenyl-3-(phenylimino)-4,7-dihydro- 3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylates: Synthesis and Agrochemical Studies
Authors: Dotsenko, V. V.
Доценко, В. В.
Aksenov, N. A.
Аксенов, Н. А.
Aksenova, I. V.
Аксенова, И. В.
Keywords: [1,2]dithiolo[3,4-b]pyridines;Herbicide safeners;Active methylene thioamides;Michael addition;Dithiomalondianilide;Cyanoacetic esters
Issue Date: 2023
Citation: Dotsenko, V.V., Sinotsko, A.E., Strelkov, V.D., Varzieva, E.A., Russkikh, A.A., Levchenko, A.G., Temerdashev, A.Z., Aksenov, N.A., Aksenova, I.V. Alkyl 4-Aryl-6-amino-7- phenyl-3-(phenylimino)-4,7-dihydro- 3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylates: Synthesis and Agrochemical Studies // Molecules. - 2023. - 28(2), art. no. 609. - DOI: 10.3390/molecules28020609.
Series/Report no.: Molecules
Abstract: The reaction between dithiomalondianilide (N,N’-diphenyldithiomalondiamide) and alkyl 3-aryl-2-cyanoacrylates in the presence of morpholine in the air atmosphere leads to the formation of alkyl 6-amino-4-aryl-7-phenyl-3-(phenylimino)-4,7-dihydro-3H-[1,2]dithiolo[3,4-b]- pyridine-5-carboxylates in 37–72% yields. The same compounds were prepared in 23–65% yields by ternarycondensation of aromatic aldehydes, ethyl(methyl) cyanoacetate and dithiomalondianilide. The reaction mechanism is discussed. The structure of ethyl 6-amino-4-(4-methoxyphenyl)-7-phenyl-3-(phenylimino)-4,7-dihydro-3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylate was confirmed by X-ray crystallography. Two of the prepared compounds showed a moderate growth-stimulating effect on sunflower seedlings. Three of the new compounds were recognized as strong herbicide safeners with respect to herbicide 2,4-D in the laboratory and field experiments on sunflower.
URI: http://hdl.handle.net/20.500.12258/23489
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

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