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Title: Synthesis of 2-carboxyaniline-substituted maleimides from 2'-nitrochalcones
Authors: Aksenov, N. A.
Аксенов, Н. А.
Aksenov, D. A.
Аксенов, Д. А.
Ganusenko, D. D.
Ганусенко, Д. Д.
Kurenkov, I. A.
Куренков, И. А.
Leontiev, A. V.
Леонтьев, А. В.
Aksenov, A. V.
Аксенов, А. В.
Keywords: Fluorescent probes;3-anilino-4-(het)arylmaleimides;β-substituted α-aminomaleimides
Issue Date: 2023
Citation: Aksenov N.A., Aksenov D.A., Ganusenko D.D., Kurenkov I.A., Leontiev A.V., Aksenov A.V. Synthesis of 2-carboxyaniline-substituted maleimides from 2'-nitrochalcones // Organic & biomolecular chemistry. - 2023. - 21(15), pp. 3156-3166. - DOI: 10.1039/d3ob00197k
Series/Report no.: Organic and Biomolecular Chemistry
Abstract: A practical, one-pot approach to 3-anilino-4-(het)arylmaleimides by simple heating of aqueous DMSO solution of 2′-nitrochalcones with potassium cyanide in the presence of formic acid has been developed. This new reaction provides effective access to a variety of β-substituted α-aminomaleimides which have recently become a subject of growing interest as small, easily modified and environmentally responsive fluorescent probes.
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

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