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Title: Novel Two-Step Synthesis of N -Alkylated 2,3-Diaryl-4-quinolones
Authors: Aksenov, A. V.
Аксенов, А. В.
Arutiunov, N. A.
Арутюнов, Н. А.
Zatsepilina, A. M.
Зацепилина, А. М.
Aksenova, A. A.
Аксенова, А. А.
Aleksandrova, E. V.
Александрова, Е. В.
Aksenov, N. A.
Аксенов, Н. А.
Leontiev, A. V.
Леонтьев, А. В.
Aksenov, D. A.
Аксенов, Д. А.
Keywords: 4-quinolones;Nitroalkenes;Cascade transformations;Indoles;Rearrangement;Sodium compounds
Issue Date: 2023
Citation: Aksenov, A.V., Arutiunov, N.A., Zatsepilina, A.M., Aksenova, A.A., Aleksandrova, E.V., Aksenov, N.A., Leontiev, A.V., Aksenov, D.A. Novel Two-Step Synthesis of N -Alkylated 2,3-Diaryl-4-quinolones // Synthesis (Germany). - 2023. - 56 (3). - pp. 435-444. - DOI: 10.1055/s-0042-1751530
Series/Report no.: Synthesis (Germany)
Abstract: A library of 18 polysubstituted 4-quinolones was conveniently prepared via simple and practical protocol involving N-alkylation of 2-(3-oxoindolin-2-yl)acetonitriles and following NaH-induced ring expansion. The current two-step approach provides feasible access to a subclass of N-protected C3-aryl-substituted 2-phenyl-4-quinolones starting with or just one step away from commercially available 2- arylindoles and nitrostyrenes.
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

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