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|Title:||Nutritional supplement for control of diabetes|
|Authors:||Selimov, M. A.|
Селимов, М. А.
Nagdalian, A. A.
Нагдалян, А. А.
Sadovoy, V. V.
Садовой, В. В.
Shchedrina, T. V.
Щедрина, Т. В.
|Keywords:||Brewer's yeast;Chromium chelate;Diabetes;Lecithin;Vitamins;Selen-active|
|Publisher:||International Pharmaceutical Excipients Council (IPEC)|
|Citation:||Sadovoy, V.V., Selimov, M.A., Shchedrina, T.V., Nagdalian, A.A. Nutritional supplement for control of diabetes // Journal of Excipients and Food Chemicals. - 2017. - Volume 8. - Issue 2. - Pages 31-38|
|Series/Report no.:||Journal of Excipients and Food Chemicals|
|Abstract:||The analysis of diabetic patients’ dietary habits indicate that there is an imbalance of selected vitamins and minerals. A nutrient supplement composition, intended for prophylactic administration, was developed to correct this imbalance. It was composed of dried eggs and a yeast component (60%), vitamin Â1 (0.02%) and nicotinamide (0.04%), chromium chelate (0.02%), “selen-active” (0.02%) and lecithin (39.9%). The dried eggs and yeast component were prepared by the homogenization of lysozyme rich chicken eggs and yeast followed by storage and drying at a pre-defined temperature and to a set water content respectively. The nutritional supplement was incorporated at 5% concentration into a sausage recipe which was subsequently cooked into animal feed. An assessment of the safety and efficacy of the prophylactic nutritional supplement was performed in an alloxan induced diabetic rat model. The developed composition, as a part of the animal feed, improved metabolic processes, increased antioxidant activity, reduced lipid peroxidation, decreased blood cholesterol, and improved carbohydrate metabolism in the experimental animals|
|Appears in Collections:||Статьи, проиндексированные в SCOPUS, WOS|
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