Influence of the Chlorophytum comosum leaves hydroalcoholic extract on some representatives of intestinal microflora of rats

Abstract

The present study was conducted to evaluate the effect of Chlorophytum comosum (C. comosum) extract on some of the main representatives of the intestine microflora of rats. The I Group of test animals received C. comosum alcoholic extract for 10 days at the concentration of 5 mg/kg body weight per rat. In the II Group was intestinal dysbiosis induced by gentamicin sulfate, they received the C. comosum extract in the same dose. The III Group of animals also with dysbiosis received only a standard diet. After the termination of the oral administration of gentamicin the animals of the III Group was divided on two sub-group, and animals of the second one (experimental) received C. comosum extract for 10 days. Feeding of hydroalcoholic extract of C. comosum leaves has no effect on the number of representatives of Bifidobacterium spp, Lactobacillus spp during its free reception or with an induced dysbiosis. However, the feeding of the extract promotes moderate stimulation of Escherichia coli with normal enzymatic activity and reduction of Candida spp. This allows to recommend C. comosum extract as a support means in cases of dysbacteriosis associated with lack of E. coli, as well as to reduce the overly high number of Candida spp