Please use this identifier to cite or link to this item:
https://dspace.ncfu.ru/handle/20.500.12258/3085
Title: | STUDY OF POLYLAYER DIETARY FIBER BASED CAPSULES BEHAVIOR UNDER ENZYMATIC HYDROLYSIS IN VITRO |
Authors: | Evdokimov, I. A. Евдокимов, И. А. |
Keywords: | Capsules;Enzymatic hydrolysis in vitro;Alginate;Carboxymethyl cellulose;Mechanical properties;Swelling |
Issue Date: | 2017 |
Publisher: | IRKUTSK NATL RESEARCH TECHNICAL UNIV |
Citation: | Rasumova, LS; Evteev, AV; Bannikova, AV; Evdokimov, IA. STUDY OF POLYLAYER DIETARY FIBER BASED CAPSULES BEHAVIOR UNDER ENZYMATIC HYDROLYSIS IN VITRO // IZVESTIYA VUZOV-PRIKLADNAYA KHIMIYA I BIOTEKHNOLOGIYA. - 2017. - Том: 7. - Выпуск: 1. - Стр.: 148-154 |
Series/Report no.: | IZVESTIYA VUZOV-PRIKLADNAYA KHIMIYA I BIOTEKHNOLOGIYA |
Abstract: | The aim of this work was to study the behavior of single and multilayer capsules from sodium alginate and CMC during enzymatic hydrolysis in-vitro. Multilayer capsules based on the dietary fiber with encapsulated model biologically active protein were developed. Their behavior was studied under conditions of enzymatic hydrolysis in vitro using physical methods of analysis. It is shown that the capsules size was followed the reduction trends in the model "stomach." However, after being placed in an intestinal solution all capsules began to swell to varying degrees due to an increase in electrostatic repulsion forces. During the experiment, it was found that the hardness of the capsules in a model "stomach" was higher as compared to their mechanical properties in a model "intestine", followed by the destruction of capsules at the end of intestinal phase. It is noted that the multilayer capsule had the greatest ability to protect the encapsulated model biologically active protein in acidic gastric environment. The results of this analysis indicate that the changes in the mechanical properties and the swelling behavior of capsules based on dietary fiber provide a relationship to the control release of encapsulated bioactive components |
URI: | http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=28&SID=C5bLhL1kLpq2QVtos25&page=1&doc=1 http://hdl.handle.net/20.500.12258/3085 |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
WoS 192 .pdf Restricted Access | 821.65 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.