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Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/326
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dc.contributor.authorDotsenko, V. V.-
dc.contributor.authorДоценко, В. В.-
dc.date.accessioned2018-05-28T14:07:12Z-
dc.date.available2018-05-28T14:07:12Z-
dc.date.issued2018-
dc.identifier.citationPalchykov, V.A., Chabanenko, R.M., Konshin, V.V., Dotsenko, V.V., Krivokolysko, S.G., Chigorina, E.A., Horak, Y.I., Lytvyn, R.Z., Vakhula, A.A., Obushak, M.D., Mazepa, A.V. Dihydro-2: H -thiopyran-3(4 H)-one-1,1-dioxide-a versatile building block for the synthesis of new thiopyran-based heterocyclic systems // New Journal of Chemistry. - 2018. - Volume 42. - Issue 2. - pp. 1403-1412.ru
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85040867684&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=nort*+caucas*+fed*+univ*&sid=ee04ec9a017c9031934f6a9ca119a70b&sot=afnl&sdt=sisr&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Dihydro+2H+thiopyran+3%284H%29+one+1%2c1+dioxide+-+a+versatile+building+block+for+the+synthesis+of+new+thiopyran%29&relpos=0&citeCnt=0&searchTerm=-
dc.identifier.urihttps://dspace.ncfu.ru:443/handle/20.500.12258/326-
dc.description.abstractThree series of new cyclic sulfones have been prepared by a one-pot multi-component reaction (MCR) starting from the readily available dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide. The in silico screening of the synthesized compounds revealed their high anti-inflammatory, antiarthritic, antiasthmatic and antiallergic potential coupled with the strong probability levels of cystinyl aminopeptidase inhibition. The key structures were confirmed by 2D NMR techniquesru
dc.language.isoenru
dc.publisherRoyal Society of Chemistryru
dc.relation.ispartofseriesNew Journal of Chemistry-
dc.subjectBeta-keto sulfonesru
dc.subjectAtp channel openersru
dc.subjectBiological-activityru
dc.subject3-component synthesisru
dc.subjectBladder contractionsru
dc.titleDihydro-2: H -thiopyran-3(4 H)-one-1,1-dioxide-a versatile building block for the synthesis of new thiopyran-based heterocyclic systemsru
dc.typeСтатьяru
vkr.amountPages 1403-1412ru
vkr.instИнститут математики и естественных наук-
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

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