Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/3330
Title: Direct and facile synthesis of 9-aminoacridine and acridin-9-yl-ureas
Authors: Borovlev, I. V.
Боровлев, И. В.
Demidov, O. P.
Демидов, О. П.
Amangasieva, G. A.
Амангазиева, Г. А.
Avakyan, E. K.
Авакян, Е. К.
Keywords: Facile synthesis;Direct synthesis;9-aminoacridine;Acridin-9-yl-ureas
Issue Date: 2016
Publisher: Elsevier Ltd
Citation: Borovlev, I.V., Demidov, O.P., Amangasieva, G.A., Avakyan, E.K. Direct and facile synthesis of 9-aminoacridine and acridin-9-yl-ureas // Tetrahedron Letters. - 2016. - Volume 57. - Issue 32. - Pages 3608-3611
Series/Report no.: Tetrahedron Letters
Abstract: The ability of urea anions to react as nucleophiles with acridine has been investigated. An effective SNH synthesis of 9-aminoacridine was developed using the urea/NaH/DMSO system. However, when mono substituted ureas containing bulky substituents or 1,1-dialkyl substituted ureas were used, products of the SNH reaction of alkyl carbamoyl amination were obtained. Single crystal structure and the tautomerism of selected compound were studied
URI: https://www.scopus.com/record/display.uri?eid=2-s2.0-84978224689&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=94a185ef2a894025076dc32df599dd02&sot=afnl&sdt=cl&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=89&citeCnt=4&searchTerm=
http://hdl.handle.net/20.500.12258/3330
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