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https://dspace.ncfu.ru/handle/20.500.12258/3330| Title: | Direct and facile synthesis of 9-aminoacridine and acridin-9-yl-ureas |
| Authors: | Borovlev, I. V. Боровлев, И. В. Demidov, O. P. Демидов, О. П. Amangasieva, G. A. Амангазиева, Г. А. Avakyan, E. K. Авакян, Е. К. |
| Keywords: | Facile synthesis;Direct synthesis;9-aminoacridine;Acridin-9-yl-ureas |
| Issue Date: | 2016 |
| Publisher: | Elsevier Ltd |
| Citation: | Borovlev, I.V., Demidov, O.P., Amangasieva, G.A., Avakyan, E.K. Direct and facile synthesis of 9-aminoacridine and acridin-9-yl-ureas // Tetrahedron Letters. - 2016. - Volume 57. - Issue 32. - Pages 3608-3611 |
| Series/Report no.: | Tetrahedron Letters |
| Abstract: | The ability of urea anions to react as nucleophiles with acridine has been investigated. An effective SNH synthesis of 9-aminoacridine was developed using the urea/NaH/DMSO system. However, when mono substituted ureas containing bulky substituents or 1,1-dialkyl substituted ureas were used, products of the SNH reaction of alkyl carbamoyl amination were obtained. Single crystal structure and the tautomerism of selected compound were studied |
| URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-84978224689&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=94a185ef2a894025076dc32df599dd02&sot=afnl&sdt=cl&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=89&citeCnt=4&searchTerm= http://hdl.handle.net/20.500.12258/3330 |
| Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| scopusresults 506 .pdf Restricted Access | 62.2 kB | Adobe PDF | View/Open | |
| WoS 300 .pdf Restricted Access | 103.73 kB | Adobe PDF | View/Open |
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