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https://dspace.ncfu.ru/handle/20.500.12258/3445
Title: | Metal-templated assembly of cyclopropane-fused diazepanones and diazecanones via exo- trig nucleophilic cyclization of cyclopropenes with tethered carbamates |
Authors: | Rubin, M. A. Рубин, М. А. |
Keywords: | Metal-Templated Assembly;Nucleophilic Cyclization;Tethered Carbamates |
Issue Date: | 2018 |
Publisher: | American Chemical Society |
Citation: | Maslivetc, V.A., Frolova, L.V., Rogelj, S., Maslivetc, A.A., Rubina, M., Rubin, M. Metal-Templated Assembly of Cyclopropane-Fused Diazepanones and Diazecanones via exo- trig Nucleophilic Cyclization of Cyclopropenes with Tethered Carbamates // Journal of Organic Chemistry. - 2018. - статья в печати |
Series/Report no.: | Journal of Organic Chemistry |
Abstract: | A strain-release-driven, cation-templated nucleophilic 7- and 8-exo-trig-cyclization of tethered Boc-protected amines to cyclopropenes is described. The featured reaction proceeds in diastereo- and regioselective fashion and allows for preparation of the corresponding 2,5-diazabicyclo[5.1.0]octan-6-ones and 2,6-diazabicyclo[6.1.0]nonan-7-ones as sole products in high yields. Preliminary studies on anticancer activities of these novel cyclopropane-fused medium heterocycles were performed |
URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-85056148282&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=6bb4e38e48c5091ac82975132bd42355&sot=afnl&sdt=sisr&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Metal-Templated+Assembly+of+Cyclopropane-Fused+Diazepanones+and+Diazecanones+via+exo-+trig+Nucleophilic+Cyclization+of+Cyclopropenes+with+Tethered+Carbamates%29&relpos=0&citeCnt=0&searchTerm= http://hdl.handle.net/20.500.12258/3445 |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
File | Description | Size | Format | |
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scopusresults 611 .pdf Restricted Access | 62.05 kB | Adobe PDF | View/Open | |
WoS 420 .pdf Restricted Access | 106.37 kB | Adobe PDF | View/Open |
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