Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12258/3475
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAksenov, N. A.-
dc.contributor.authorАксенов, Н. А.-
dc.contributor.authorAksenov, A. V.-
dc.contributor.authorАксенов, А. В.-
dc.contributor.authorAksenov, D. A.-
dc.contributor.authorАксенов, Д. А.-
dc.contributor.authorOvcharov, S. N.-
dc.contributor.authorОвчаров, С. Н.-
dc.contributor.authorRubin, M. A.-
dc.contributor.authorРубин, М. А.-
dc.date.accessioned2018-11-23T12:19:13Z-
dc.date.available2018-11-23T12:19:13Z-
dc.date.issued2018-
dc.identifier.citationAksenov, N.A., Aksenov, A., Kornienko, A., De Carvalho, A., Mathieu, V., Aksenov, D.A., Ovcharov, S.N., Griaznov, G.D., Rubin, M. A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities // RSC Advances. - 2018. - Volume 8. - Issue 64. - Pages 36980-36986ru
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85056392927&origin=resultslist&sort=plf-f&src=s&st1=A+nitroalkane-based+approach+to+one-pot+three-component+synthesis+of+isocryptolepine+and+its+analogs+with+potent+anti-cancer+activities&st2=&sid=24b550a4004eff540c1f66bf75dbf431&sot=b&sdt=b&sl=150&s=TITLE-ABS-KEY%28A+nitroalkane-based+approach+to+one-pot+three-component+synthesis+of+isocryptolepine+and+its+analogs+with+potent+anti-cancer+activities%29&relpos=0&citeCnt=0&searchTerm=-
dc.identifier.urihttp://hdl.handle.net/20.500.12258/3475-
dc.description.abstractA second generation polyphosphoric acid-mediated one-pot three-component synthesis of indoloquinoline scaffold is developed. This improved version of the process involves electrophilically activated nitroalkanes for the installation of strategic C-C and C-N bonds and ring C assembly. This modification allows the elimination of unnecessary solvent change operations and all steps are carried out in a true, uninterrupted one-pot manner. A further improvement involves the possibility to install an ortho-amino group in situ. A synthetic application of this method is showcased by the concise synthesis of an isocryptolepine alkaloid and its synthetic analogs with potent anticancer activitiesru
dc.language.isoenru
dc.publisherROYAL SOC CHEMISTRYru
dc.relation.ispartofseriesRSC Advances-
dc.subjectAnticancer activityru
dc.subjectChange operationsru
dc.subjectConcise synthesisru
dc.subjectPolyphosphoric acidsru
dc.subjectSecond generationru
dc.subjectSynthetic analogsru
dc.subjectSynthetic applicationru
dc.subjectThree componentru
dc.titleA nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activitiesru
dc.typeСтатьяru
vkr.amountPages 36980-36986ru
vkr.instИнститут математики и естественных наук-
vkr.instИнститут нефти и газа-
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

Files in This Item:
File Description SizeFormat 
scopusresults 626 .pdf62.46 kBAdobe PDFThumbnail
View/Open
WoS 365 .pdf907.69 kBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.