Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12258/4260
Title: Nonalcoholic steatohepatitis animal model, induced by high-fat diet and tetracycline
Authors: Timchenko, L. D.
Тимченко, Л. Д.
Rzhepakovsky, I. V.
Ржепаковский, И. В.
Keywords: High-fat diet;Liver;Nonalcoholic steatohepatitis;Tetracycline
Issue Date: 2015
Publisher: Canadian Center of Science and Education
Citation: Areshidze, D.A., Timchenko, L.D., Syomin, I.A., Kozlova, M.A., Rzhepakovsky, Igor. V. Nonalcoholic steatohepatitis animal model, induced by high-fat diet and tetracycline // Modern Applied Science. - 2015. - Volume 9. - Issue 1. - Pages 170-177
Series/Report no.: Modern Applied Science
Abstract: As a result of research it was succeeded to receive the model of non-alcoholic steatohepatitis which is characterized by obesity, violation of the structural organization, a fabric necrosis, formation of fibrosis of a liver. The developed model of non-alcoholic steatohepatitis allows to study also staging of development of a fatty desease of the liver which is characterized by formation of a steatogepatitis and fibrosis. In quality the inducing factors the high-fat diet and antibiotics were used. The offered NASH model can be used in the field of chronic experiments for an assessment of extent of violation of a functional condition of hepatobiliary system and for search of the effective pharmacotheurapeutichepatoprotective agents
URI: https://www.scopus.com/record/display.uri?eid=2-s2.0-84920144724&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=c504db1c362651ae731a7fd05a4f01a2&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222015%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Nonalcoholic+steatohepatitis+animal+model%2c+induced+by+high-fat+diet+and+tetracycline%29&relpos=0&citeCnt=1&searchTerm=
http://hdl.handle.net/20.500.12258/4260
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