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|Title:||Nonalcoholic steatohepatitis animal model, induced by high-fat diet and tetracycline|
|Authors:||Timchenko, L. D.|
Тимченко, Л. Д.
Rzhepakovsky, I. V.
Ржепаковский, И. В.
|Keywords:||High-fat diet;Liver;Nonalcoholic steatohepatitis;Tetracycline|
|Publisher:||Canadian Center of Science and Education|
|Citation:||Areshidze, D.A., Timchenko, L.D., Syomin, I.A., Kozlova, M.A., Rzhepakovsky, Igor. V. Nonalcoholic steatohepatitis animal model, induced by high-fat diet and tetracycline // Modern Applied Science. - 2015. - Volume 9. - Issue 1. - Pages 170-177|
|Series/Report no.:||Modern Applied Science|
|Abstract:||As a result of research it was succeeded to receive the model of non-alcoholic steatohepatitis which is characterized by obesity, violation of the structural organization, a fabric necrosis, formation of fibrosis of a liver. The developed model of non-alcoholic steatohepatitis allows to study also staging of development of a fatty desease of the liver which is characterized by formation of a steatogepatitis and fibrosis. In quality the inducing factors the high-fat diet and antibiotics were used. The offered NASH model can be used in the field of chronic experiments for an assessment of extent of violation of a functional condition of hepatobiliary system and for search of the effective pharmacotheurapeutichepatoprotective agents|
|Appears in Collections:||Статьи, проиндексированные в SCOPUS, WOS|
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