Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/693
Title: Aminomethylation of Guareschi imides: synthesis of 2,4-dioxo-1H,5H-3,7-spiro[diazabicyclo[3.3.1]nonane-9,4'-piperidine]-1,5-dicarbonitriles
Authors: Dotsenko, V. V.
Доценко, В. В.
Aksenov, N. A.
Аксенов, Н. А.
Aksenova, I. V.
Аксенова, И. В.
Keywords: 2,6-Dioxopiperidine-3,5-dicarbonitriles;3,7-Diazabicyclo[3.3.1]nonanes;3,9-diazaspiro[5.5]undecane;Aminomethylation;Bispidines;Guareschi imides;Mannich reaction
Issue Date: 2017
Publisher: Springer New York LLC
Citation: Khrustaleva, A.N., Frolov, K.A., Dotsenko, V.V., Aksenov, N.A., Aksenova, I.V., Krivokolysko, S.G. Aminomethylation of Guareschi imides: synthesis of 2,4-dioxo-1H,5H-3,7-spiro[diazabicyclo[3.3.1]nonane-9,4'-piperidine]-1,5-dicarbonitriles // Chemistry of Heterocyclic Compounds. - 2017. - Volume 53. - Issue 8. - pp. 887-891
Series/Report no.: Chemistry of Heterocyclic Compounds
Abstract: The aminomethylation reaction of 9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile hydrochloride in the presence of primary aliphatic amines and an excess of 37% aqueous formaldehyde led to the formation of 7-substituted 1'-benzyl-2,4-dioxo-1H,5Hspiro[3,7-diazabicyclo[3.3.1]nonane-9,4'-piperidine]-1,5-dicarbonitrile derivatives
URI: https://www.scopus.com/record/display.uri?eid=2-s2.0-85030720306&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=nort*+caucas*+fed*&sid=67baa13f81fb80c2720f291e8bebd3a4&sot=afnl&sdt=cl&cluster=scopubyr%2c%222017%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=38&citeCnt=0&searchTerm=
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