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https://dspace.ncfu.ru/handle/20.500.12258/7502
Title: | Michael addition to 3-(2-nitrovinyl)indoles – route toward aliphatic nitro compounds with heterocyclic substituents |
Authors: | Aksenov, N. A. Аксенов, Н. А. Skomorokhov, A. A. Скоморохов, А. А. Aksenov, A. V. Аксенов, А. В. Rubin, M. A. Рубин, М. А. |
Keywords: | Indole;Isoxazole;Michael addition;Microwave-assisted synthesis;Nitroalkenes;Pyrazole |
Issue Date: | 2019 |
Publisher: | Springer New York LLC |
Citation: | Aksenov, N.A., Skomorokhov, A.A., Aksenov, A.V., Voskressensky, L.G., Rubin, M.A. Michael addition to 3-(2-nitrovinyl)indoles – route toward aliphatic nitro compounds with heterocyclic substituents // Chemistry of Heterocyclic Compounds. - 2019. - Volume 55. - Issue 6. - Pages 541-546 |
Series/Report no.: | Chemistry of Heterocyclic Compounds |
Abstract: | Synthetic approach toward indole derivatives bearing 2-nitroethyl group and polar azole moiety has been developed. This method involves conjugate addition of 1,3-dicarbonyl compounds to 3-(2-nitrovinyl)-1H-indoles followed by cyclocondensation with hydrazine or hydroxylamine to furnish pyrazole or isoxazole ring. Application of microwave activation allows to obtain the target indole derivatives in short time and avoid protection of indole nitrogen atom |
URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-85070100471&origin=resultslist&sort=plf-f&src=s&st1=Michael+addition+to+3-2-nitrovinyl+indoles+--+route+toward+aliphatic+nitro+compounds+with+heterocyclic+substituents&st2=&sid=1c5a6fe41babdcf93eed0c3d463275ee&sot=b&sdt=b&sl=130&s=TITLE-ABS-KEY%28Michael+addition+to+3-2-nitrovinyl+indoles+--+route+toward+aliphatic+nitro+compounds+with+heterocyclic+substituents%29&relpos=0&citeCnt=0&searchTerm= http://hdl.handle.net/20.500.12258/7502 |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
File | Description | Size | Format | |
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WoS 680 .pdf Restricted Access | 104.58 kB | Adobe PDF | View/Open | |
scopusresults 1024 .pdf Restricted Access | 133.46 kB | Adobe PDF | View/Open |
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