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|Title:||THE NEW EFFICIENCY OF THE "SRMP" - LISTERIAS GROWTH-PROMOTING FACTOR DURING FACTORY CULTIVATION|
|Authors:||Sizonenko, M. N.|
Сизоненко, М. Н.
Timchenko, L. D.
Тимченко, Л. Д.
Rzhepakovsky, I. V.
Ржепаковский, И. В.
Piskov, S. I.
Писков, С. И.
Nagdalian, A. A.
Нагдалян, А. А.
Povetkin, S. N.
Поветкин, С. Н.
|Keywords:||Microorganisms' growth-promoting factor;Vaccine;Listeria monocytogenes;Lyophilization;Protective drying environment;Cultivation|
|Publisher:||JADOUN SCIENCE PUBLISHING GROUP|
|Citation:||Sizonenko, MN; Timchenko, LD; Rzhepakovskiy, IV; Piskov, SI; Areshidze, DA; Mikhailenko, VV; Nagdalian, AA; Simonov, AN; Svetlakova, EV; Verevkina, MN; Povetkin, SN. THE NEW EFFICIENCY OF THE "SRMP" - LISTERIAS GROWTH-PROMOTING FACTOR DURING FACTORY CULTIVATION // PHARMACOPHORE. - 2019. - Том: 10. - Выпуск: 2. - Стр.: 85-88|
|Abstract:||Despite the established technological regulations and clearly tried-and-true vaccine production mechanisms, there are certain difficulties both in the cultivation process and at the stage of freeze-drying, including" dry live vaccine from the "AUF" strain against the farm animals' listeriosis". Listeria growth-promoting factor "SRMP" was tested on the quails' egg embryonic tissue at different stages of preparation of the vaccine against the farm animals' listeriosis. The addition of 1% SRMP to the Hottinger's agar was effective at all the factory cultivation stages, and the mass of the Listeria monocytogenes, cultivated in the fermenter, increased by 25%. The addition of 1% SRMP to the drying environment of the vaccine against the farm animals' listeriosis enabled the microorganisms survival increase after lyophilization by 13% compared to the factory vaccine. Even after 12 months of vaccine storage, the Listeria survival rate in the vaccine with 13.3% SRMP was higher than in the factory vaccine|
|Appears in Collections:||Статьи, проиндексированные в SCOPUS, WOS|
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