ANTIOXIDANT ACTIVITY OF NEW SYNTHESIZED PYRIMIDINONE DERIVATIVES

Abstract

Pharmacological properties of pyrimidinones have been studied in relation to the antioxidant activity. All the sodium salts of hydroxystyryl derivatives exhibit pronounced antioxidant activity in contrast to 2,6-dialkylsulfamide derivatives of pyrimidin-4(1H)-one. Screening of antioxidant activity has shown that compounds containing vanillin residues IIa and o-vanillin residues IIc are the leading compounds.