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Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/11979
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dc.contributor.authorShcherbakov, S. V.-
dc.contributor.authorЩербаков, С. В.-
dc.contributor.authorMagometov, A. Y.-
dc.contributor.authorМагометов, А. Ю.-
dc.contributor.authorShcherbakova, V. Y.-
dc.contributor.authorЩербакова, В. Ю.-
dc.contributor.authorAksenov, A. V.-
dc.contributor.authorАксенов, А. В.-
dc.contributor.authorRubin, M. A.-
dc.contributor.authorРубин, М. А.-
dc.date.accessioned2020-06-16T10:17:11Z-
dc.date.available2020-06-16T10:17:11Z-
dc.date.issued2020-
dc.identifier.citationShcherbakov, S.S., Magometov, A.Y., Shcherbakova, V.Y., Aksenov, A.V., Domenyuk, D.A., Zelensky, V.A., Rubin, M. Electrophilic alkylation of arenes with 5-bromopyrimidine en route to 4-aryl-5-alkynylpyrimidines // RSC Advances. - 2020. - Volume 10. - Issue 17. - Pages 10315-10321ru
dc.identifier.urihttp://hdl.handle.net/20.500.12258/11979-
dc.description.abstractA new synthetic protocol for preparation of medicinally important 4-aryl-5-alkynylpyrimidines is described. The featured approach involves a sequence of chemo- and regioselective Brønsted acid-catalyzed electrophilic alkylation of arenes with 5-bromopyrimidine, followed by oxidative re-aromatization of the formed dihydropyrimidine ring. Finally, palladium-catalyzed Sonogashira cross-coupling reaction provided an end-game strategyru
dc.language.isoenru
dc.publisherRoyal Society of Chemistryru
dc.relation.ispartofseriesRSC Advances-
dc.subjectAromatic hydrocarbonsru
dc.subjectCatalysisru
dc.subjectElectrophilic alkylationsru
dc.subjectSynthetic protocolsru
dc.subjectAlkylationru
dc.subjectPalladium-catalyzedru
dc.titleElectrophilic alkylation of arenes with 5-bromopyrimidine en route to 4-aryl-5-alkynylpyrimidinesru
dc.typeСтатьяru
vkr.instИнститут математики и естественных наукru
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