Synthesis of 2-(1H-Indol-2-yl)acetamides via bronsted acid-assisted cyclization cascade

Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/14565

Title:	Synthesis of 2-(1H-Indol-2-yl)acetamides via bronsted acid-assisted cyclization cascade
Authors:	Aksenov, N. A. Аксенов, Н. А. Aksenov, D. A. Аксенов, Д. А. Skomorokhov, A. A. Скоморохов, А. А. Prityko, L. A. Притыко, Л. А. Aksenov, A. V. Аксенов, А. В. Griaznov, G. D. Грязнов, Г. Д. Rubin, M. A. Рубин, М. А.
Keywords:	2'-aminochalcones;Efficient;Michael addition;Histone;Discovery;Indoles;Reduction;Inhibitory-activity;Nitrostyrenes;Route
Issue Date:	2020
Publisher:	AMER CHEMICAL SOC
Citation:	Aksenov, NA; Aksenov, DA; Skomorokhov, AA; Prityko, LA; Aksenov, AV; Griaznov, GD; Rubin, M. Synthesis of 2-(1H-Indol-2-yl)acetamides via bronsted acid-assisted cyclization cascade // JOURNAL OF ORGANIC CHEMISTRY. - 2020. - Том: 85. - Выпуск: 19. - Стр.: 12128-12146
Series/Report no.:	Journal of Organic Chemistry
Abstract:	An efficient and straightforward Bronsted-acid mediated cascade process was developed, involving cyclization of readily available beta-ketonitriles into 2-aminofurans, and their subsequent recyclization into 2-(1H-indol-2-yl)acetamides is developed. This synthetic route opens a new avenue for an expeditious assembly of
URI:	http://hdl.handle.net/20.500.12258/14565
Appears in Collections:	Статьи, проиндексированные в SCOPUS, WOS

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