The use of principal component analysis for evaluation of morphofunctional changes in red blood cells under the influence of different glucose conecntrations

Abstract

The article presents findings of the research investigating the effect of various glucose concentrations on the morphometric parameters ofred blood cells. The principal component method was employed in order to determine the most significant indicators in the experiment. The experiment was aimed to investigate the effect of hyperglycemia on the shape, size and functional parameters of erythrocytes depending on the glucose concentration and exposure time. It was established that characteristic changes in the shape and size of erythrocytes induced by hyperglycemia are correlative with concentration of glucose and exposure time