Please use this identifier to cite or link to this item:
https://dspace.ncfu.ru/handle/20.500.12258/15477
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Dotsenko, V. V. | - |
dc.contributor.author | Доценко, В. В. | - |
dc.contributor.author | Aksenov, N. A. | - |
dc.contributor.author | Аксенов, Н. А. | - |
dc.contributor.author | Aksenova, I. V. | - |
dc.contributor.author | Аксенова, И. В. | - |
dc.date.accessioned | 2021-03-18T12:52:15Z | - |
dc.date.available | 2021-03-18T12:52:15Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Dotsenko, V.V., Khrustaleva, A.N., Frolov, K.A., Aksenov, N.A., Aksenova, I.V., Krivokolysko, S.G. 1,6-Diamino-2-oxopyridine-3,5-dicarbonitrile Derivatives in the Mannich Reaction // Russian Journal of General Chemistry. - 2021. - Volume 91. - Issue 1. - Pages 44-56 | ru |
dc.identifier.uri | http://hdl.handle.net/20.500.12258/15477 | - |
dc.description.abstract | 1,6-Diamino-2-oxo-1,2,3,4-tetrahydropyridine-3,5-dicarbonitriles under the action of primary aliphatic amines and an excess of 37% formalin in ethanol were converted into 2,3,8,9-tetrahydro-6,10-methano[1,2,4]triazolo[1,5-a][1,5]diazocine-6,10(7H)-dicarbonitrile derivatives. At the same time, the Mannich reaction in the case of 1,6-diamino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles proceeds ambiguously, and, depending on the conditions, gives either N-ethoxymethylation products or 1,2,4-triazolo[1,5-a]pyridine derivatives. In silico predictive analysis of the biological activity of new compounds was carried out | ru |
dc.language.iso | en | ru |
dc.publisher | Pleiades journals | ru |
dc.relation.ispartofseries | Russian Journal of General Chemistry | - |
dc.subject | 1,2,4-triazolo[1,5-a]pyridines | ru |
dc.subject | 2-cyanoacethydrazide | ru |
dc.subject | 3,7-diazabicyclo[3.3.1]nonanes | ru |
dc.subject | aminomethylation | ru |
dc.subject | Mannich reaction | ru |
dc.title | 1,6-Diamino-2-oxopyridine-3,5-dicarbonitrile Derivatives in the Mannich Reaction | ru |
dc.type | Статья | ru |
vkr.inst | Химико-фармацевтический факультет | ru |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
scopusresults 1605 .pdf Restricted Access | 856.33 kB | Adobe PDF | View/Open | |
WoS 1025 .pdf Restricted Access | 138.74 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.