Репозиторий научных и учебно-методических публикаций
Северо-Кавказский федеральный университет
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https://dspace.ncfu.ru/handle/20.500.12258/2446| Title: | Unexpected cyclization of 2-(2-aminophenyl)indoles with nitroalkenes to furnish indolo[3,2-: C] quinolines |
| Authors: | Aksenov, A. V. Аксенов, А. В. Aksenov, D. A. Аксенов, Д. А. Griaznov, G. D. Грязнов, Г. Д. Aksenov, N. A. Аксенов, Н. А. Rubin, M. A. Рубин, М. А. |
| Keywords: | Positive ions;CDK inhibitors;Mechanistic pathways;Mediated reactions;Nitroalkenes;Polyphosphoric acids;Synthetic study;Chemistry |
| Issue Date: | 2018 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Aksenov, A.V., Aksenov, D.A., Griaznov, G.D., Aksenov, N.A., Voskressensky, L.G., Rubin, M. Unexpected cyclization of 2-(2-aminophenyl)indoles with nitroalkenes to furnish indolo[3,2-: C] quinolines // Organic and Biomolecular Chemistry. - 2018. - Volume 16. - Issue 23. - Pages 4325-4332 |
| Series/Report no.: | Organic and Biomolecular Chemistry |
| Abstract: | The polyphosphoric acid-mediated reaction of 2-(2-aminophenyl)indenes with nitroalkenes was tested in the frame of synthetic studies towards CDK inhibitors with the paullone core. Unexpectedly, this reaction proceeded via a different mechanistic pathway affording derivatives of the natural alkaloid isocryptolepine. The scope of this unusual transformation was investigated and a mechanistic rationale explaining this outcome is offered |
| URI: | https://dspace.ncfu.ru:443/handle/20.500.12258/2446 |
| Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| scopusresults 135 .pdf Restricted Access | 63.08 kB | Adobe PDF | View/Open | |
| WoS 74 .pdf Restricted Access | 76.9 kB | Adobe PDF | View/Open |
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