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Title: | One-pot, three-component assembly of indoloquinolines: total synthesis of isocryptolepine |
Authors: | Aksenov, A. V. Аксенов, А. В. Aksenov, D. A. Аксенов, Д. А. Orazova, N. A. Оразова, Н. А. Aksenov, N. A. Аксенов, Н. А. Griaznov, G. D. Грязнов, Г. Д. Rubin, M. A. Рубин, М. А. |
Keywords: | Anti-proliferative activities;Chemistry;Arylhydrazines;Synthetic analogues;Synthetic application;Three component;Total synthesis |
Issue Date: | 2017 |
Publisher: | American Chemical Society |
Citation: | Aksenov, A.V., Aksenov, D.A., Orazova, N.A., Aksenov, N.A., Griaznov, G.D., De Carvalho, A., Kiss, R., Mathieu, V., Kornienko, A., Rubin, M. One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine // Journal of Organic Chemistry. - 2017. - Volume 82. - Issue 6. - Pages 3011-3018 |
Series/Report no.: | Journal of Organic Chemistry |
Abstract: | Indolo[3,2-c]quinolones have been efficiently synthesized via an acid-mediated, one-pot, three-component condensation of arylhydrazines, o-aminoacetophenones, and triazines or nitriles. The synthetic application of this method is showcased by the concise synthesis of isocryptolepine alkaloid and a series of its synthetic analogues with demonstrated cancer cell antiproliferative activities |
URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-85015621562&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=ed251e00f055bf6a464fa9575f335a90&sot=aff&sdt=sisr&sl=174&s=AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29+OR+AF-ID%28%22Stavropol+State+University%22+60070961%29+OR+AF-ID%28%22stavropolskij+Gosudarstvennyj+Tehniceskij+Universitet%22+60026323%29&ref=%28One-Pot%2c+Three-Component+Assembly+of+Indoloquinolines%3a+Total+Synthesis+of+Isocryptolepine%29&relpos=2&citeCnt=4&searchTerm= http://hdl.handle.net/20.500.12258/3070 |
Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
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scopusresults 357 .pdf Restricted Access | 62.71 kB | Adobe PDF | View/Open | |
WoS 180 .pdf Restricted Access | 106.95 kB | Adobe PDF | View/Open |
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