Репозиторий научных и учебно-методических публикаций
Северо-Кавказский федеральный университет
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https://dspace.ncfu.ru/handle/20.500.12258/3070| Title: | One-pot, three-component assembly of indoloquinolines: total synthesis of isocryptolepine |
| Authors: | Aksenov, A. V. Аксенов, А. В. Aksenov, D. A. Аксенов, Д. А. Orazova, N. A. Оразова, Н. А. Aksenov, N. A. Аксенов, Н. А. Griaznov, G. D. Грязнов, Г. Д. Rubin, M. A. Рубин, М. А. |
| Keywords: | Anti-proliferative activities;Chemistry;Arylhydrazines;Synthetic analogues;Synthetic application;Three component;Total synthesis |
| Issue Date: | 2017 |
| Publisher: | American Chemical Society |
| Citation: | Aksenov, A.V., Aksenov, D.A., Orazova, N.A., Aksenov, N.A., Griaznov, G.D., De Carvalho, A., Kiss, R., Mathieu, V., Kornienko, A., Rubin, M. One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine // Journal of Organic Chemistry. - 2017. - Volume 82. - Issue 6. - Pages 3011-3018 |
| Series/Report no.: | Journal of Organic Chemistry |
| Abstract: | Indolo[3,2-c]quinolones have been efficiently synthesized via an acid-mediated, one-pot, three-component condensation of arylhydrazines, o-aminoacetophenones, and triazines or nitriles. The synthetic application of this method is showcased by the concise synthesis of isocryptolepine alkaloid and a series of its synthetic analogues with demonstrated cancer cell antiproliferative activities |
| URI: | http://hdl.handle.net/20.500.12258/3070 |
| Appears in Collections: | Статьи, проиндексированные в SCOPUS, WOS |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| scopusresults 357 .pdf Restricted Access | 62.71 kB | Adobe PDF | View/Open | |
| WoS 180 .pdf Restricted Access | 106.95 kB | Adobe PDF | View/Open |
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