Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/3077
Title: Synthesis of thiazolo[3,2-a]pyridines via an unusual Mannich-type cyclization
Authors: Dotsenko, V. V.
Доценко, В. В.
Keywords: Aminomethylation;Bis(pyrid-2-yl)disulfides;Mannich reaction;Thiazolo[3,2-a]pyridines;X-ray studies
Issue Date: 2017
Publisher: Taylor and Francis Ltd.
Citation: Dotsenko, V.V., Bushmarinov, I.S., Goloveshkin, A.S., Chigorina, E.A., Frolov, K.A., Krivokolysko, S.G. Synthesis of thiazolo[3,2-a]pyridines via an unusual Mannich-type cyclization // Phosphorus, Sulfur and Silicon and the Related Elements. - 2017. - Volume 192. - Issue 1. - Pages 47-52
Series/Report no.: Phosphorus, Sulfur and Silicon and the Related Elements
Abstract: The Mannich-type reaction of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates with 3-(1,3-benzodioxol-5-yl)-2-methylpropanal (ocean propanal) and p-toluidine afforded 7-aryl-2-(1,3-benzodioxol-5-ylmethyl)-2-methyl-3-[(4-methylphenyl)amino]-5-oxo-2,3,6,7-tetrahydro-5H-thiazolo[3,2-a]pyridine-8-carbonitriles in modest (25–46%) yields. The structure of the key compound was confirmed by X-ray crystal structure analysis
URI: https://www.scopus.com/record/display.uri?eid=2-s2.0-84992129583&origin=resultslist&sort=plf-f&src=s&st1=Synthesis+of+thiazolo%5b3%2c2-a%5dpyridines+via+an+unusual+Mannich-type+cyclization&st2=&sid=60eedcc0553c9716e061af579858b0e1&sot=b&sdt=b&sl=92&s=TITLE-ABS-KEY%28Synthesis+of+thiazolo%5b3%2c2-a%5dpyridines+via+an+unusual+Mannich-type+cyclization%29&relpos=0&citeCnt=3&searchTerm=
http://hdl.handle.net/20.500.12258/3077
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