Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12258/14853
Title: Preparation of spiro[indole-3,5′-isoxazoles] via Grignard conjugate addition/spirocyclization sequence
Authors: Aksenov, A. V.
Аксенов, А. В.
Aksenov, D. A.
Аксенов, Д. А.
Aksenov, N. A.
Аксенов, Н. А.
Skomorokhov, A. A.
Скоморохов, А. А.
Aleksandrova, E. V.
Александрова, Е. В.
Rubin, M. A.
Рубин, М. А.
Keywords: Addition reactions;Reagents;Alkyl-substituted derivatives;Polycyclic aromatic hydrocarbons
Issue Date: 2021
Publisher: Royal Society of Chemistry
Citation: Aksenov, A.V., Aksenov, D.A., Aksenov, N.A., Skomorokhov, A.A., Aleksandrova, E.V., Rubin, M. Preparation of spiro[indole-3,5′-isoxazoles] via Grignard conjugate addition/spirocyclization sequence // RSC Advances. - 2021. - Volume 11. - Issue 3. - Pages 1783-1793
Series/Report no.: RSC Advances
Abstract: A highly efficient one-pot procedure combining conjugate addition of Grignard reagents to (2-nitroalkenyl)indoles and sub-sequent Brønsted acid-assisted spirocyclization allowed for preparation of 4′H-spiro[indole-3,5′-isoxazoles] in a diastereomerically selective fashion. Utilization of alkyl Grignard reagents provided an easy access to 4′-alkylsubstituted derivatives hardly available by other means
URI: http://hdl.handle.net/20.500.12258/14853
Appears in Collections:Статьи, проиндексированные в SCOPUS, WOS

Files in This Item:
File Description SizeFormat 
scopusresults 1540 .pdf866.19 kBAdobe PDFView/Open
WoS 1003 .pdf259.08 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.