Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles

Please use this identifier to cite or link to this item: https://dspace.ncfu.ru/handle/20.500.12258/19508

Title:	Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles
Authors:	Aksenov, N. A. Аксенов, Н. А. Aksenov, A. V. Аксенов, А. В. Prityko, L. A. Притыко, Л. А. Aksenov, D. A. Аксенов, Д. А. Aksenova, D. S. Аксенова, Д. С. Rubin, M. A. Рубин, М. А.
Keywords:	Oxidative cyclization;Oxidation of the aniline moiety;Nucleophilic intramolecular cyclization
Issue Date:	2022
Publisher:	American Chemical Society
Citation:	Aksenov, N. A., Aksenov, A. V., Prityko, L. A., Aksenov, D. A., Aksenova, D. S., Nobi, M. A., Rubin, M. Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles // ACS Omega. - 2022. - DOI10.1021/acsomega.2c01238
Series/Report no.:	ACS Omega
Abstract:	A facile and highly efficient method for the preparation of 2-(3-oxoindolin-2-ylidene)acetonitriles from 4-(2-aminophenyl)-4-oxo-2-phenylbutanenitriles is described. The featured transformation operates via nucleophilic intramolecular cyclization and involves oxidation of the aniline moiety. Overall, this modification allowed for the improvement of yields and expansion of the reaction scope.
URI:	http://hdl.handle.net/20.500.12258/19508
Appears in Collections:	Статьи, проиндексированные в SCOPUS, WOS

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